Functional analysis using whole-genome sequencing of a drug-sensitive Mycobacterium tuberculosis strain from Peru

D. Tarazona; V. Borda; M. Galarza; J. C. Agapito; H. Guio

doi:10.1128/genomeA.e00087-14

Functional analysis using whole-genome sequencing of a drug-sensitive Mycobacterium tuberculosis strain from Peru

D. Tarazona
, V. Borda
, M. Galarza
, J. C. Agapito
, H. Guio

Producción científica: Contribución a una revista › Artículo › revisión exhaustiva

2 Citas (Scopus)

Resumen

We report the whole-genome sequence of a Latin American-Mediterranean (LAM) lineage drug-sensitive Mycobacterium tuberculosis strain from Peru, INS-SEN. The functional analysis revealed more mutations in secondary metabolite biosynthesis, transport, and catabolism (clusters of orthologous groups [COG] category Q) than for other LAM-sensitive strains. This study contributes to the understanding of the genomic diversity of drug-sensitive M. tuberculosis.

Idioma original	Inglés
Número de artículo	e00087-14
Publicación	Genome Announcements
Volumen	2
N.º	1
DOI	https://doi.org/10.1128/genomeA.e00087-14
Estado	Publicada - 2014
Publicado de forma externa	Sí

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abstract = "We report the whole-genome sequence of a Latin American-Mediterranean (LAM) lineage drug-sensitive Mycobacterium tuberculosis strain from Peru, INS-SEN. The functional analysis revealed more mutations in secondary metabolite biosynthesis, transport, and catabolism (clusters of orthologous groups [COG] category Q) than for other LAM-sensitive strains. This study contributes to the understanding of the genomic diversity of drug-sensitive M. tuberculosis.",

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AU - Guio, H.

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Functional analysis using whole-genome sequencing of a drug-sensitive Mycobacterium tuberculosis strain from Peru

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