TOWARDS THE SEPARATION OF MALARIA INFECTED RED BLOOD CELLS USING LOW-COST MICROFLUIDICS

Nicolas Thorne; Luis Flores-Olazo; Julio Valdivia-Silva; Danny van Noort

TOWARDS THE SEPARATION OF MALARIA INFECTED RED BLOOD CELLS USING LOW-COST MICROFLUIDICS

Nicolas Thorne, Luis Flores-Olazo, Julio Valdivia-Silva, Danny van Noort

Department of Bioengineering and Chemical Engineering

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

Abstract

To step up the diagnosis of malaria in remote areas of the Amazon in Peru, our group has started to develop low-cost inertial microfluidic devices, fabricated using standard 3D printers. Initial results show a 1-step separation of 7 and 10 μm beads at a 40% and 84% separation rate, while red blood cells were separated at 40%. Our goal is to perform multi-step separation of patients' blood, followed by diagnosis using an impedance analyser to detect Plasmodium infected red blood cells which can be utilised in remote clinics.

Original language	English
Title of host publication	MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
Publisher	Chemical and Biological Microsystems Society
Pages	1195-1196
Number of pages	2
ISBN (Electronic)	9781733419031
State	Published - 2021
Event	25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 - Palm Springs, Virtual, United States Duration: 10 Oct 2021 → 14 Oct 2021

Publication series

Name	MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference	25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Country/Territory	United States
City	Palm Springs, Virtual
Period	10/10/21 → 14/10/21

Keywords

3D printing
Plasmodium spp
low-cost microfluidics
malaria
red blood cells

Cite this

Thorne, N., Flores-Olazo, L., Valdivia-Silva, J., & van Noort, D. (2021). TOWARDS THE SEPARATION OF MALARIA INFECTED RED BLOOD CELLS USING LOW-COST MICROFLUIDICS. In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences (pp. 1195-1196). (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences). Chemical and Biological Microsystems Society.

Thorne, Nicolas ; Flores-Olazo, Luis ; Valdivia-Silva, Julio et al. / TOWARDS THE SEPARATION OF MALARIA INFECTED RED BLOOD CELLS USING LOW-COST MICROFLUIDICS. MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2021. pp. 1195-1196 (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

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title = "TOWARDS THE SEPARATION OF MALARIA INFECTED RED BLOOD CELLS USING LOW-COST MICROFLUIDICS",

abstract = "To step up the diagnosis of malaria in remote areas of the Amazon in Peru, our group has started to develop low-cost inertial microfluidic devices, fabricated using standard 3D printers. Initial results show a 1-step separation of 7 and 10 μm beads at a 40% and 84% separation rate, while red blood cells were separated at 40%. Our goal is to perform multi-step separation of patients' blood, followed by diagnosis using an impedance analyser to detect Plasmodium infected red blood cells which can be utilised in remote clinics.",

keywords = "3D printing, Plasmodium spp, low-cost microfluidics, malaria, red blood cells",

author = "Nicolas Thorne and Luis Flores-Olazo and Julio Valdivia-Silva and {van Noort}, Danny",

note = "Publisher Copyright: {\textcopyright} 2021 MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. All rights reserved.; 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 ; Conference date: 10-10-2021 Through 14-10-2021",

year = "2021",

language = "English",

series = "MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

publisher = "Chemical and Biological Microsystems Society",

pages = "1195--1196",

booktitle = "MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences",

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Thorne, N, Flores-Olazo, L, Valdivia-Silva, J & van Noort, D 2021, TOWARDS THE SEPARATION OF MALARIA INFECTED RED BLOOD CELLS USING LOW-COST MICROFLUIDICS. in MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, Chemical and Biological Microsystems Society, pp. 1195-1196, 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021, Palm Springs, Virtual, United States, 10/10/21.

TOWARDS THE SEPARATION OF MALARIA INFECTED RED BLOOD CELLS USING LOW-COST MICROFLUIDICS. / Thorne, Nicolas; Flores-Olazo, Luis; Valdivia-Silva, Julio et al.
MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society, 2021. p. 1195-1196 (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

Research output: Chapter in Book/Report/Conference proceeding › Conference contribution › peer-review

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AU - Valdivia-Silva, Julio

AU - van Noort, Danny

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N2 - To step up the diagnosis of malaria in remote areas of the Amazon in Peru, our group has started to develop low-cost inertial microfluidic devices, fabricated using standard 3D printers. Initial results show a 1-step separation of 7 and 10 μm beads at a 40% and 84% separation rate, while red blood cells were separated at 40%. Our goal is to perform multi-step separation of patients' blood, followed by diagnosis using an impedance analyser to detect Plasmodium infected red blood cells which can be utilised in remote clinics.

AB - To step up the diagnosis of malaria in remote areas of the Amazon in Peru, our group has started to develop low-cost inertial microfluidic devices, fabricated using standard 3D printers. Initial results show a 1-step separation of 7 and 10 μm beads at a 40% and 84% separation rate, while red blood cells were separated at 40%. Our goal is to perform multi-step separation of patients' blood, followed by diagnosis using an impedance analyser to detect Plasmodium infected red blood cells which can be utilised in remote clinics.

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KW - Plasmodium spp

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KW - malaria

KW - red blood cells

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BT - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

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ER -

Thorne N, Flores-Olazo L, Valdivia-Silva J, van Noort D. TOWARDS THE SEPARATION OF MALARIA INFECTED RED BLOOD CELLS USING LOW-COST MICROFLUIDICS. In MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences. Chemical and Biological Microsystems Society. 2021. p. 1195-1196. (MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences).

TOWARDS THE SEPARATION OF MALARIA INFECTED RED BLOOD CELLS USING LOW-COST MICROFLUIDICS

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