Functional analysis using whole-genome sequencing of a drug-sensitive Mycobacterium tuberculosis strain from Peru

D. Tarazona; V. Borda; M. Galarza; J. C. Agapito; H. Guio

doi:10.1128/genomeA.e00087-14

Functional analysis using whole-genome sequencing of a drug-sensitive Mycobacterium tuberculosis strain from Peru

D. Tarazona
, V. Borda
, M. Galarza
, J. C. Agapito
, H. Guio

Research output: Contribution to journal › Article › peer-review

2 Scopus citations

Abstract

We report the whole-genome sequence of a Latin American-Mediterranean (LAM) lineage drug-sensitive Mycobacterium tuberculosis strain from Peru, INS-SEN. The functional analysis revealed more mutations in secondary metabolite biosynthesis, transport, and catabolism (clusters of orthologous groups [COG] category Q) than for other LAM-sensitive strains. This study contributes to the understanding of the genomic diversity of drug-sensitive M. tuberculosis.

Original language	English
Article number	e00087-14
Journal	Genome Announcements
Volume	2
Issue number	1
DOIs	https://doi.org/10.1128/genomeA.e00087-14
State	Published - 2014
Externally published	Yes

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title = "Functional analysis using whole-genome sequencing of a drug-sensitive Mycobacterium tuberculosis strain from Peru",

abstract = "We report the whole-genome sequence of a Latin American-Mediterranean (LAM) lineage drug-sensitive Mycobacterium tuberculosis strain from Peru, INS-SEN. The functional analysis revealed more mutations in secondary metabolite biosynthesis, transport, and catabolism (clusters of orthologous groups [COG] category Q) than for other LAM-sensitive strains. This study contributes to the understanding of the genomic diversity of drug-sensitive M. tuberculosis.",

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AU - Guio, H.

PY - 2014

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AB - We report the whole-genome sequence of a Latin American-Mediterranean (LAM) lineage drug-sensitive Mycobacterium tuberculosis strain from Peru, INS-SEN. The functional analysis revealed more mutations in secondary metabolite biosynthesis, transport, and catabolism (clusters of orthologous groups [COG] category Q) than for other LAM-sensitive strains. This study contributes to the understanding of the genomic diversity of drug-sensitive M. tuberculosis.

UR - https://www.scopus.com/pages/publications/84998880996

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Functional analysis using whole-genome sequencing of a drug-sensitive Mycobacterium tuberculosis strain from Peru

Abstract

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